Human orphan cytochrome p450 2u1 catalyzes the -hydroxylation of leukotriene b4

HIGHLIGHTS

  • who: Khawla Nouri and colleagues from the Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR, Universitu00e9 Paris Citu00e9, rue des Saints-Pu00e8res, Paris, France have published the Article: Human Orphan Cytochrome P450 2U1 Catalyzes the -Hydroxylation of Leukotriene B4, in the Journal: (JOURNAL)
  • what: The analysis of the data invited the authors to focus on leukotriene B4 (LTB4 ) an important inflammatory mediator. The authors show that CYP2U1 efficiently catalyzes the hydroxylation of LTB4 predominantly on its u03c9-position.
  • how: Cytochrome P450 2U1 (CYP2U1) identified from the human genome remains poorly known . . .

     

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