Human papillomavirus downregulates the expression of ifitm1 and ripk3 to escape from ifnγ- and tnfα-mediated antiproliferative effects and necroptosis

HIGHLIGHTS

  • who: Sjoerd H. van der Burg from the Brunel University London, UK have published the article: Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFNγ- and TNFα-Mediated Antiproliferative Effects and Necroptosis, in the Journal: (JOURNAL)
  • what: The authors evaluated the influence of hrHPV on the IFNγ- and TNFα-mediated cell growth inhibition and cell death induction of undifferentiated KCs by functional and biochemical assays. The authors show that hrHPV-infected KCs resist the immune system by interfering with the regulation of intracellular growth and cell death programs of infected cells . . .

     

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