HIGHLIGHTS
- who: Asian Pac J Cancer and colleagues from the HPVs are exclusively intraepithelial pathogens, which can infect the cutaneous and mucosal squamous epithelium and cause both benign and malignant hyperproliferative lesions (Stanley, )The mechanism of carcinogenicity in papillomaviruses depends on the role of , and , oncoproteins, which degrade two major cellular tumor suppressor proteins, that is, p, and retinoblastoma tumor suppressor protein (pRb), respectively (Yim and Park, ). Considering the oncogenic characteristics of HPV, its genotypes can be divided into high-risk HPV (HR-HPV) and low-risk HPV (Ahmed et_al, ). Persistent HRHPV types, including HPV, , and, are associated . . .
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