Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

HIGHLIGHTS

• who: Matthias Paulus Wagner from the Pasteur, Universitu00e9 de Paris, Malaria Parasite Biology and Vaccines Unit, Paris, France Technological University have published the Article: Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target, in the Journal: (JOURNAL) of June/14,/2022
• what: The authors demonstrate falciparum imports a host antioxidant enzyme peroxiredoxin 6 (PRDX6) during hemoglobin uptake from the red blood cell cytosol. The authors show that P. falciparum internalizes host RBC PRDX6 along with hemoglobin during blood-stage parasite development. The authors demonstrate that lipid peroxidation repair by . . .
  

   

  

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