Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis

HIGHLIGHTS

  • who: Tui Neri from the U- Italy, University have published the research: Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Leveraging embryology data across species, the authors report that human pluripotent stem_cells are able to recapitulate the developmental process of valvulogenesis. The authors report that these cells collectively or at the single cell level express a set of salient genes that mark pre-EMT (E9.0) mouse AVC. The authors show here that HPVCs derived from pluripotent stem_cells accurately reflect the . . .

     

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