Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor a chain, epithelial-to-mesenchymal transition

HIGHLIGHTS

  • who: Receptor A Chain and collaborators from the Institut National, Université Paris-Sud, Hôpital Paul Brousseper Ricerca sul Cancro, Italy have published the research work: Human Renal Cancer Cells Express a Novel Membrane-Bound Interleukin-15 that Induces, in Response to the Soluble Interleukin-15 Receptor A Chain, Epithelial-to-Mesenchymal Transition, in the Journal: (JOURNAL) of February/15,/2009
  • what: The authors show a significant increase of ERK1/2 phosphorylation in RCC7 cells treated with at least 100 ng/mL of s-IL-15Ra (Fig 3A). This study reports that human RCC constitutively . . .

     

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