Human sialic acid o-acetyl esterase (siae) – mediated changes in sensitivity to etoposide in a medulloblastoma cell line

HIGHLIGHTS

• who: Rebecca L. Mather and colleagues from the University of Portsmouth, Brain Tumour Research Centre, School of Pharmacy and Biomedical Sciences, St have published the article: Human Sialic acid O-acetyl esterase (SIAE) - mediated changes in sensitivity to etoposide in a medulloblastoma cell line, in the Journal: Scientific Reports Scientific Reports of 15/05/2019
• what: The authors show that the GD3 acetylation pathway is dysregulated in MB and as a proofof-principle the authors show that increased GD3 expression sensitises an MB cell line to etoposide.
• how: As GD3A is thought to . . .
  

   

  

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