Human-type sialic acid receptors contribute to avian influenza a virus binding and entry by hetero-multivalent interactions

HIGHLIGHTS

  • who: Mengying Liu from the Department University, Utrecht, The Netherlands have published the Article: Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that, by hetero-multivalent binding, synthetic sialoglycans which by themselves cannot support binding can compensate for insufficient amounts of preferred receptors for avian as well as human IAV strains. To confirm that heteromultivalent binding can have a positive effect on binding of other avian IAVs the authors show similar effects on an . . .

     

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