Hupz, a unique heme-binding protein, enhances group a streptococcus fitness during mucosal colonization

HIGHLIGHTS

• who: Kristin V. Lyles from the Department of Biology, Georgia State University, Atlanta, GA, United States, Binghamton Biofilm Research Center have published the article: HupZ, a Unique Heme-Binding Protein, Enhances Group A Streptococcus Fitness During Mucosal Colonization, in the Journal: (JOURNAL)
• what: The authors investigate heme-binding and degradation by HupZ expressed without a His6 tag and use mutagenesis, heterologous expression, and a mice model to probe the protein`s function in_vivo. The authors examined HupZ`s function using biochemical and genetic approaches.
• how: Similar observations were made with the heme-degrading . . .
  

   

  

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