Hur plays a role in double-strand break repair in pancreatic cancer cells and regulates functional brca1-associated- ring-domain-1(bard1) isoforms

HIGHLIGHTS

• who: Aditi Jain and collaborators from the Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA have published the research work: HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated- Ring-Domain-1(BARD1) Isoforms, in the Journal: (JOURNAL)
• what: Using an established double-strand-break repair assay (pDR-GFP), the authors demonstrate for the first time that HuR directly affects HRR activity in PDAC cells . A Subset of DDR Genes Are Targets of HuR: BARD1 Is a Novel HuR Target To follow up on . . .
  

   

  

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