HIGHLIGHTS
- who: Virginie Vauthier from the Universitu00e9 Paris Citu00e9, CNRS, INSERM, Institut Cochin, Rue Mu00e9chain, Paris, France have published the research: HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine, in the Journal: (JOURNAL) of 18/05/2022
- what: The authors provide evidence that the phosphorylation is conducted by a Cyclin/ CDK1 complex like that of SAMHD1 at T592. Altogether the authors show that TASOR phosphorylation occurs in vivo on T819. The authors focus on the TASOR residue T819 since this amino_acid has been detected phosphorylated in proteomic analyses and because TASOR T819 lies . . .
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