Huwe1 supports b-cell development, b-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation

HIGHLIGHTS

• who: Aldo Spanjaard et al. from the (IRCM), Canada Friedrich Schiller University Jena have published the article: Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation, in the Journal: (JOURNAL)
• what: The authors aimed to delineate the relevance of the E3 ligase HUWE1, also known as Mule or ARF-BP1 in B-cell-dependent immunity. The study demonstrates the complexity of Huwe-1 in controlling cell proliferation.
• how: The authors showed that human GC B cells are characterized by low protein expression of POLB . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.