HIGHLIGHTS
- who: Iwona Niemietz and Kelly L. Brown from the University of Milano-Bicocca, Italy have published the article: Hyaluronan promotes intracellular ROS production and apoptosis in TNFu03b1-stimulated neutrophils, in the Journal: (JOURNAL)
- what: Building on the previous report of HA as a novel and atypical priming agent for fMLF-induced ROS production by neutrophils , herein the authors demonstrate that HA can prime neutrophils for an augmented oxidative burst in response to classical endogenous and exogenous agonists (receptor and non-receptor mediated) other than fMLF, namely C5a and PMA. To priming neutrophils, the authors provide . . .
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