HIGHLIGHTS
- who: Xiaoqing Miao and collaborators from the College, Shandong University, Weihai, China have published the research work: Hyaluronidase Promote Transdermal Diffusion of Small Sized Curcumin Nanocrystal by Dissolving Microneedles Delivery, in the Journal: Pharmaceutics 2023, 788 of /2023/
- what: The authors focused on the HAase to depolymerize the HA and loosen the ECM barrier.
SUMMARY
The mechanism of CUR works on skin involved as follows: when the medium evaporates, continuous aqueous menisci are generated between CUR particles and skin, triggering local swelling of the skin and achieving highly passive penetration of . . .
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