Hybrid autoencoder with orthogonal latent space for robust population structure inference

HIGHLIGHTS

  • who: Meng Yuan from the DepartmentUniversity Hospitals have published the Article: Hybrid autoencoder with orthogonal latent space for robust population structure inference, in the Journal: Scientific Reports Scientific Reports
  • what: The authors proposed a hybrid method for population structure inference, SAE-IBS, which yields an orthogonal latent space, like matrix decomposition-based methods, and can extract more comprehensive latent features by exploiting the non-linear nature of neural_network-based methods. Motivation, the authors propose to include an extra robust projection loss (mathematical details in additional file 1) in the original objective function, yielding a denoising . . .

     

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