Hybrid biopolymer and lipid nanoparticles with improved transfection efficacy for mrna

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  • who: Christian D. Siewert et al. from the Department of Pharmaceutics and Biopharmaceutics, Johannes Gutenberg University Mainz, Johannes Gutenberg University, Mainz, Germany have published the article: Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA, in the Journal: Cells 2020, 9, It 2034 10 of 19 state. appears that the protamine competed with DOTAP for RNA binding, and a certain fraction of /2020/
  • what: With the experiments , the different transfection signals of mRNA within the hybrid nanoparticles could be directly correlated with different structural morphologies obtained from varying the assembly procedure and the . . .

     

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