Hybrid molecules containing naphthoquinone and quinolinedione scaffolds as antineoplastic agents

HIGHLIGHTS

  • who: Ines Mancini and collaborators from the Laboratory of Bioorganic Chemistry, Department of Physics, University of Trento, Trento, Italy have published the paper: Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents, in the Journal: Molecules 2022, 4948 of /2022/
  • what: This work aims at summarizing the current knowledge on antitumor hybrids built using 1 4- and 1 (present in natural compounds lawsone napabucasin plumbagin lapachol u03b1-lapachone and u03b2 -lapachone) and the related quinolone- and isoquinolinedione reported in the literature up to 2021. Molecular hybridization is the term that best represents the purpose . . .

     

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