Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase*

HIGHLIGHTS

• who: Bart A. van der Veen from the (UNIVERSITY) have published the research work: Hydrophobic Amino Acid Residues in the Acceptor Binding Site Are Main Determinants for Reaction Mechanism and Specificity of Cyclodextrin-glycosyltransferase*, in the Journal: (JOURNAL) of September/12,/2001
• how: The study indeed shows that the various residues have distinct roles dependent on whether disproportionation cyclization or coupling reactions take place.

SUMMARY

To investigate this in detail the authors altered the acceptor site residues Lys-232, Phe-183, Phe-259, and Glu-264 of Bacillus circulans strain 251 . . .

 



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