Hydrophobicity of arginine leads to reentrant liquid-liquid phase separation behaviors of arginine-rich proteins

HIGHLIGHTS

  • who: Yuri Hong from the (UNIVERSITY) have published the paper: Hydrophobicity of arginine leads to reentrant liquid-liquid phase separation behaviors of arginine-rich proteins, in the Journal: (JOURNAL) of 14/Nov/2022
  • what: The authors show that arginine`s ability to promote LLPS is independent of the presence of aromatic partners, and that arginine-rich peptides, but not lysine-rich peptides, display re-entrant phase behavior at high salt concentrations. The aim of the study is to elucidate the competing roles of electrostatic interactions and hydrophobicity in driving LLPS using model systems purposefully stripped . . .

     

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