HIGHLIGHTS
- who: Andreas Meyer from the Indole by Laboratory have published the research: Hydroxylation of Indole by Laboratory-evolved 2-Hydroxybiphenyl 3-Monooxygenase*, in the Journal: (JOURNAL) of June/27,/2002
- what: The authors report the characterization of HbpAind with respect to its catalytic properties.
SUMMARY
The wild-type protein does not catalyze these reactions. The activity for indole hydroxylation was increased 18-fold in this variant. Concomitantly, the Kd value for indole decreased from 1.5 mM to 78 M. Investigation of the major reaction products of HbpAind with indole revealed . . .
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