Hydroxylpropyl-cyclodextrin as potential excipient to prevent stress-induced aggregation in liquid protein formulations

HIGHLIGHTS

  • who: Tanja Stolzke et al. from the Laboratory of Thermodynamics, Department of Biochemical and Chemical Engineering, TU Dortmund University, Dortmund, Germany have published the research work: Hydroxylpropyl-cyclodextrin as Potential Excipient to Prevent Stress-Induced Aggregation in Liquid Protein Formulations, in the Journal: Molecules 2022, 5094 of /2022/
  • what: In a best-case scenario these excipients fulfil multiple demands simultaneously such increasing long-term stability of the formulation reducing adsorption on surfaces/interfaces and stabilizing the against thermal or mechanical stress. (derivative of holds this potential but has not yet been sufficiently investigated for use . . .

     

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