Hyper sensitive protein detection by tandem-htrf reveals cyclin d1 dynamics in adult mouse

HIGHLIGHTS

  • who: Alexandre Zampieri from the CNRSof Excellence from genome and epigenome to molecular medicine (EpiGenMed), Montpellier, France have published the research work: Hyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse, in the Journal: Scientific Reports Scientific Reports
  • what: The authors focused on testis because spermatogonia are in constant proliferation to generate the precursors of terminally differentiated sperm cells25.
  • how: To further establish the benefit of Tandem-HTRF as a semi-quantitative method for protein abundance assessment the authors used a known stabilizing mutation of CycD1 on Threonine . . .

     

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