HIGHLIGHTS
SUMMARY
Similarly, circulating neutrophil counts are elevated in severely ill patients, and higher neutrophil-to-lymphocyte ratios are associated with poor prognosis. NETs are elevated in the plasma of severe patients and correlate with lung failure and immunothrombosis (25, 31, 32, 33 Preprint), whereas isolated neutrophils from COVID-19 patients vol 6 | no 2 | e202201658 1 of 13 display elevated rates of both ROS production and NETosis. The authors performed a detailed multidimensional flow cytometry analysis and proteomic characterization of circulating neutrophils in patients with COVID-19. COVID-19 patients exhibit a pattern of systemic . . .
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