Hyperexcitability of sensory neurons in fragile x mouse model

HIGHLIGHTS

  • who: Valeria Cavalli and Vitaly A. Klyachko from the Department of Cell Biology and Physiology, Washington University School of Medicine, StLouis, MO, United States have published the research: Hyperexcitability of Sensory Neurons in Fragile X Mouse Model, in the Journal: (JOURNAL)
  • what: The authors performed recordings from the DRG neurons isolated from adolescent mice in a short-term culture to examine changes in sensory neuron excitability caused by loss of FMRP.

SUMMARY

    Individuals with FXS commonly exhibit somatosensory deficits, such as hypersensitivity to touch (Cascio, 2010), Self-injurious behaviors in Fragile . . .

     

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