Hyperglycemia-induced oxidative stress and epigenetic regulation of et-1 gene in endothelial cells

HIGHLIGHTS

  • who: April and collaborators from the King Abdulaziz University, Saudi Arabia have published the paper: Hyperglycemia-induced oxidative stress and epigenetic regulation of ET-1 gene in endothelial cells, in the Journal: (JOURNAL)
  • what: The authors demonstrate that a 24 and 48 h exposure of HUVECs to high glucose significantly alter the ET-1 gene_expression.
  • how: To check the hypothesis the authors carried out promoter methylation analysis.

SUMMARY

    The increasing incidence of diabetes is a growing concern, causing a huge death toll and disability worldwide (Safi et_al, 2014a; Barysheva . . .

     

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