Hyperpolarized 13c-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

HIGHLIGHTS

• who: Mor Mishkovsky from the LaboratoryLausanne University have published the article: Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma, in the Journal: Scientific Reports Scientific Reports
• what: The aim of this study was to demonstrate the feasibility to monitor real-time metabolism of hyperpolarized ­[2H7,13C6]d-glucose in GBM mouse models and to employ this technique to further investigate the metabolic fate of glucose in the infiltrative zone of GBM of patient-derived xenografts in mice. The authors aimed to address the question of whether changes in glucose . . .
  

   

  

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