Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity

HIGHLIGHTS

  • who: Stavros Panagiotou from the DepartmentUniversity of have published the paper: Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity, in the Journal: Scientific Reports Scientific Reports of 14/09/2020
  • what: The authors report the unexpected finding that ST615 harbours the expression of two Ply variants i.e., a cytosolic non-haemolytic Ply and a fully haemolytic cell-wall associated Ply variant.
  • how: In view of reports suggesting that expression of Ply with low haemolytic activity could provide an early growth advantage when administered directly in ­blood19 the authors . . .

     

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