Hypoxia-induced lncrna

HIGHLIGHTS

• who: Li Zhou from the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, University, and Collaborative Innovation Center for Biotherapy, No, have published the article: Hypoxia-induced lncRNA, in the Journal: (JOURNAL)
• what: The authors identified that STEAP3AS1 is a hypoxia-responsive lncRNA, which was transcribed by HIF-1u03b1 through binding to the HREs located near the STEAP3-AS1 locus. The authors demonstrated that STEAP3-AS1 interacted with the u00adm6A reader YTHDF2 to inhibit u00adm6A-mediated degradation of STEAP3 mRNA and upregulate STEAP3 protein expression to promote CRC progression.
• how . . .
  

   

  

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