Hypoxia-inducible factor prolyl hydroxylase domain (phd) inhibition after contusive spinal cord injury does not improve locomotor recovery

HIGHLIGHTS

• who: George Z. Wei et al. from the University, UNITED STATES have published the research: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery, in the Journal: PLOS ONE of 14/09/2020
• what: This study was undertaken to determine the contributions of PHDs to ATF4-CHOP activation and white matter loss after SCI.
• how: As the ATF4-CHOP (CCAAT-enhancer-binding protein homologous protein) pathway plays a role in the pathogenesis of contusive SCI the authors examined the effects of PHD inhibition in . . .
  

   

  

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