Hypoxia inducible factors’ signaling in pediatric high-grade gliomas: role, modelization and innovative targeted approaches

HIGHLIGHTS

  • who: Quentin Fuchs and collaborators from the Pathology Department, University Hospital of Strasbourg, Moliu00e8re, Strasbourg, France have published the research work: Hypoxia Inducible Factorsu2019 Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches, in the Journal: Cancers 2020, x of /2020/
  • what: HIF-hypoxia signaling seems to be very frequently involved in each step of pHGG development or progression and might be a new path for tumorigenesis and treatment resistance understanding.
  • future: For other targeted therapies a deep knowledge on their functional inhibition will help the authors to refine accurately . . .

     

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