Hypoxia is fine-tuned by hif-1α and regulates mesendoderm differentiation through the wnt/β-catenin pathway

HIGHLIGHTS

  • who: Xiaopeng Shen from the of Major Diseases, College of Life Sciences, Anhui Normal University, Wuhu, Anhui, China have published the paper: Hypoxia is fine-tuned by Hif-1u03b1 and regulates mesendoderm differentiation through the Wnt/u03b2-catenin pathway, in the Journal: (JOURNAL)
  • what: The authors determined to investigate the effects and relationship of hypoxia and Hif-1u03b1 on the mesendoderm differentiation and Wnt/u03b2-Catenin pathway in mESCs since these remained unclear and conflicted reports existed.
  • how: The results showed that the expression of mesendoderm markers (T Eomes Mesp1 and Gsc) was . . .

     

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