Hypoxia-mediated stabilization of hif1a in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression

HIGHLIGHTS

• who: Mohamed A Abu El Maaty and collaborators from the Institut de Gu00e9nu00e9tique et de Biologie Molu00e9culaire et Cellulaire, Illkirch, France have published the paper: Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression, in the Journal: (JOURNAL) of 22/07/2022
• what: Adv. 8, eabo2295 22 July 2022 been shown to synergize with hypoxia/HIF1A signaling though activation of SMAD3 (SMAD family member 3) , the authors propose that plasticity in prostatic lesions may be driven by a cross-talk between HIF1A and ONECUT2. The authors show that TGM2 . . .
  

   

  

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