Hypoxia selects bortezomib-resistant stem cells of chronic myeloid leukemia

HIGHLIGHTS

• who: Chronic Myeloid Leukemia and collaborators from the Dipartimento di Patologia e Oncologia Sperimentali, Università degli Studi di Firenze, and Istituto Toscano Tumori, Firenze, Italy have published the research: Hypoxia Selects Bortezomib-Resistant Stem Cells of Chronic Myeloid Leukemia, in the Journal: (JOURNAL) of February/11,/2011
• what: This study showed, in primary as well as K562 CML cells, differences with respect to response to BZ between cell bulk (sensitive) and a cell subset containing LSC selected following prolonged incubation in hypoxia (resistant).
• how: The results indicated that there is no point in . . .
  

   

  

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