Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

HIGHLIGHTS

• who: Ananda S. Mirchandani from the University ofTyne, UK have published the research work: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation, in the Journal: (JOURNAL) of 18/04/2022
• what: The authors showed that monocyte recruitment and conversion into lung are required to drive inflammation resolution in hypoxic ALI. The authors show that treatment with CSF-1 increased the number of CD64hiSiglecF- and monocyte differentiation toward CD64hiSiglecF MHC-Lyve1+ a cell type that has tissue-repair roles in various disease contexts43 including in the lung11.
• how . . .
  

   

  

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