Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an nlrp3 inflammasome response in cd1c+ dendritic cells

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• who: Kurt T. K. Giuliani from the Frozen, u00b5m tissue sections were fixed with, % acetone:25% ethanol, followed by a protein blockSections were subsequently probed with primary antibodies against CD1c (Cat. No. , have published the Article: Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells, in the Journal: (JOURNAL) of 11/08/2022
• what: The authors demonstrate that patient-derived primary PTEC cultured under hypoxic conditions modelling the human CKD microenvironment: exhibit pathobiological features of ferroptotic cell death; and_(2) trigger NLRP3 inflammasome-dependent IL-1u03b2 . . .
  

   

  

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