Hypoxic mesenchymal stem cell-conditioned medium accelerates wound healing by regulating il-10 and tgf-β levels in a full-thickness-wound rat model

HIGHLIGHTS

• who: Muhar et al. from the 1. MSC isolation and characterization The procedure in this study has been approved by the Ethical Committee of Medical Faculty Sultan Agung Islamic University Semarang (approval number:, II/2020/Komisi Bioetik). The MSCs were isolated as previously described (Restimulia et_al, ). Briefly, the umbilical cord from a healthy Wistar rat at, u00adday gestational period was chopped under sterile condition and placed on a plastic flask culture. The explants were immersed in growth medium (GM) containing Dulbecco`s Modified Eagle`s Medium (DMEM) (Gibco, NY, USA) with, % fetal bovine serum (FBS) (Gibco, South . . .
  

   

  

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