HIGHLIGHTS
- who: Zhou Chen from the (UNIVERSITY) have published the Article: Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions, in the Journal: (JOURNAL) of 16/09/2022
- what: One of the main reasons why cancer cells can survive in hypoxic environments is the activation of HIFs, which reprogram metabolism, protein synthesis, and cell cycle progression .
SUMMARY
Deletion of the aryl hydrocarbon nuclear translocator (ARNT)/HIF-1β gene in CD8+ T_cells impairs the expression of cytolytic effector molecules, including perforins and granzymes. Hypoxia and T_cells A distinctive feature of T_cells is the . . .
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