HIGHLIGHTS
- who: Gustavo Ferreira Alves from the Bio-Medico University, Italy have published the research work: ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis, in the Journal: (JOURNAL)
- what: To better elucidate the molecular mechanism underlying the beneficial effects evoked by ICOS-Fc administration, the authors focused on WT mice investigating the changes in some signaling cascades, previously documented to be affected by the ICOS-ICOSL axis and, at the same time, known to exert key role in sepsis pathogenesis. The authors report for the first time molecules, and the . . .
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