Id4 is required for normal ependymal cell development

HIGHLIGHTS

  • who: Emmanuelle Huillard and Brenda Rocamonde from the University of Southern California, United States have published the paper: ID4 Is Required for Normal Ependymal Cell Development, in the Journal: (JOURNAL)
  • what: The authors show that ID4 is necessary for correct development of the LV epithelium and for correct ependymal cell maturation.
  • future: Investigation should be conducted to better understand the mechanism leading to such phenotype the potential protein partners of ID4 and the impact on neurogenesis and neuroblast migration. other mutants such as KIF3A-deficient mice (Mirzadeh et_al 2010).

SUMMARY

     

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