HIGHLIGHTS
- who: Posted Date, February and Poornimaa, Murali from the Vellore Institute of Technology: VIT University have published the paper: Identi�cation of Novel Mutant (R132H) Isocitrate Dehydrogenase 1 Inhibitors for Glioma Therapy, in the Journal: (JOURNAL)
- what: In this study approved entities of DrugBank database was explored to identify selective and potent mIDH1 inhibitors. In the study , the average root mean square deviation (RMSD) of the reference and the hit complexes were calculated for backbone atoms of the protein. This study focused on exploring plausible mIDH1 protein inhibitors using ligand similarity-based repurposing strategy.
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