HIGHLIGHTS
- who: Posted Date July et al. from the Jiangsu University of Technology have published the research: Identiufffdcation of potential inhibitors of PDE5 based on structure-based virtual screening approaches, in the Journal: (JOURNAL)
- what: In the study , an integrated virtual screening method and ADMET (Absorption, distribution, metabolism, excretion and toxicity) properties filtration were carried out to screen the natural products (NP) in the ZINC database .
- how: These results indicated that Z283 and Z171 probably bind to PDE5 with better affinity than tadalafil and the hydrophobic residues in the binding pocket are mainly responsible . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.