Identi cation of context-speci c fitness genes associated with metabolic rearrangements for prognosis and potential treatment targets for liver cancer

HIGHLIGHTS

  • who: Shizhe Yu et al. from the Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China have published the research: Identi cation of Context-Speci c Fitness Genes Associated With Metabolic Rearrangements for Prognosis and Potential Treatment Targets for Liver Cancer, in the Journal: (JOURNAL)
  • how: The authors identified fitness genes that could be used as therapeutic targets using data from CRISPR-Cas9 screens and constructed a prognostic model.

SUMMARY

    Liver cancer, mainly hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA), is the leading cause of . . .

     

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