HIGHLIGHTS
- who: . and collaborators from the University of Bergen, Norway Australia have published the paper: Identi fi cation of a signature of evolutionarily conserved stress-induced mutagenesis in cancer, in the Journal: (JOURNAL)
- what: The work shows that an increase in mutational load leads to increases in both cluster size and the percentage of SNVs involved in clusters, but only up to a point. The study provides evidence that a signature of stressinduced mutagenesis, characterized by clustering of SNVs with a defined cluster geometry, is widespread across multiple cancer types.
- how: For non-inherited . . .
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