Identification and analysis of small molecule inhibitors of crispr-cas9 in human cells

HIGHLIGHTS

• who: Yue Yang and collaborators from the MOE Key Laboratory Gene Function and Regulation and Guangzhou Key Laboratory Healthy Aging Research, School Life Sciences, Sun Yat-sen University, Guangzhou, China have published the research: Identification and Analysis of Small Molecule Inhibitors of CRISPR-Cas9 in Human Cells, in the Journal: Cells 2022, 3574 of 28/04/2019
• what: The authors aimed to identify more specific and high-affinity small-molecule inhibitors of SpCas9. Of these four compounds, C12a and C12c did not negatively affect EGFP expression in uninduced reporter 293T_cells (Supplementary Figure S3C) and 8 . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.