Identification and characterization of a transcriptional regulator for the lck proximal promoter*

HIGHLIGHTS

  • who: Atsuko Yamada from the (UNIVERSITY) have published the research work: Identification and Characterization of a Transcriptional Regulator for the lck Proximal Promoter*, in the Journal: (JOURNAL) of September/13,/2000
  • what: The authors demonstrate that a Krüppel-like zinc_finger protein, mt␤ (BFCOL1, BERF-1, ZBP-89, ZNF148), previously cloned as a protein that binds to the CD3␦ gene enhancer, binds to the ⴚ365 to ⴚ328 region of the lck proximal promoter. mt␤ is ubiquitously expressed in various cell lines and mouse tissues. The authors characterized and identified the B-factor, a potential transcriptional . . .

     

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