Identification and characterization of the wyl brxr protein and its gene as separable regulatory elements of a brex phage restriction system

HIGHLIGHTS

  • who: Yvette A. Luyten and collaborators from the University, , th Seattle, WA, USA have published the research: Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system, in the Journal: (JOURNAL)
  • what: The authors characterize a bacterial Type 1 BREX system from Acinetobacter, a bacterial genus that includes the pathogenic Acinetobacter baumanni (including a recently described pathogenic, patient-derived strain that also contains a BREX system) . The authors demonstrate that BrxR is a sequence-specific DNA binding protein comprising wHTH, WYL and WCX domains . . .

     

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