Identification and investigation of a novel nadp+-dependent secoisolariciresinol dehydrogenase from isatis indigotica

HIGHLIGHTS

  • who: Xiaoyi Shi et al. from the John Innes Centre, United Kingdom have published the research: Identification and investigation of a novel NADP+-dependent secoisolariciresinol dehydrogenase from Isatis indigotica, in the Journal: (JOURNAL)
  • what: To conclude, this study reports the first NADP+-dependent SIRD, providing theoretical support for fully expounding IiSIRD2`s catalytic characteristics and molecular mechanism, paving way for cofactor engineering, and hence having important implications regarding the efficient bioconversion of matairesinol.
  • how: The chemicals used in the experiments were reagent or High-Performance Liquid Chromatography (HPLC) grade. The molecular docking results . . .

     

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