Identification and mendelian randomization validation of pathogenic gene biomarkers in obstructive sleep apnea

HIGHLIGHTS

• What: By identifying and validating genetic markers associated with OSA, the authors seek to develop more accurate diagnostic tools and targeted therapeutic strategies, ultimately reducing the substantial health and economic burdens of this disorder. The GO analysis focused on three dimensions: biological process, cellular component, and molecular function. In the cellular component category, the primary focus was on the lysosome and azurophil granule, while molecular function emphasized iron ion binding and monooxygenase activity . Network analysis via WGCNA identified a strong association of the "MEblue" module with OSA, indicating that this module may contain key genes Frontiers in . . .
  

   

  

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