Identification and validation of a novel ferroptosis-related gene signature for prognosis and potential therapeutic target prediction in cholangiocarcinoma

HIGHLIGHTS

  • who: Apiwit Sae-fung and colleagues from the Sichuan University, China have published the research work: Identification and validation of a novel ferroptosis-related gene signature for prognosis and potential therapeutic target prediction in cholangiocarcinoma, in the Journal: (JOURNAL)
  • what: The model obtained with the training GSE89749 cohort was used to calculate each patient`s risk score in the validation cohorts. Consistent with the previous studies, the study showed that ACO1 and GOT1 were downregulated and correlated with good prognosis in CCA patients. In this study, a selective TRKA inhibitor GW441756 was shown more effective . . .

     

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