Identification and validation of novel immune-related alternative splicing signatures as a prognostic model for colon cancer

HIGHLIGHTS

  • who: Yunze Liu from the Department of Traditional Medicine, Affiliated Hospital of Xuzhou University, Xuzhou, China have published the article: Identification and Validation of Novel Immune-Related Alternative Splicing Signatures as a Prognostic Model for Colon Cancer, in the Journal: (JOURNAL)
  • what: To prevent overfitting of the model, Lasso regression was used to screen all 183 OS-ASEs. The study showed that AS alterations in IRGs significantly promoted the infiltration of most immune cells, such as M2 macrophages and CD4+ T_cells. In the study , a series of immune-related assays were conducted to verify the . . .

     

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